Lifestyle and Cardiometabolic Research Unit



Selected Publications from the LCRU (2015-2018)


*For a complete list of publications, visit Dr. Ross’ Google Scholar page.

Student authors are underlined.


Brennan AM, Benson M, Morningstar J, Herzig M, Robbins J, Gerszten RE and Ross R. Plasma metabolite profiles in response to chronic exercise. Medicine and Science in Sport and Exercise (In Press).


de Lannoy L, Sui X, Lavi CJ, Blair SN, Ross R. (2018). Change in submaximal cardiorespiratory fitness and all-cause mortalityMayo Clinic Proceedings. 93(2):184-190.


Davidson T, Vainshelboim B, Kokkinos P, Myers J, Ross R. (2017). Cardiorespiratory fitness versus physical activity as predictors of all-cause mortality in menAmerican Heart Journal. 196:156-62.


de Lannoy LClarke J, Stotz PJ, Ross R. (2017). Effects of intensity and amount of exercise on measures of insulin and glucose: Analysis of inter-individual variabilityPloS One. 12(5): e0177095


Clarke Jde Lannoy L, Ross R. (2017). Comparison of measures of maximal and submaximal fitness in response to exerciseMedicine and Science in Sports and Exercise. 49(4): 711–716.


Ko G, Davidson LE, Brennan AM, Lam M, Ross R. (2016). Abdominal adiposity, not cardiorespiratory fitness, mediates the exercise-induced change in insulin sensitivity in older adultsPloS One. 11(12): e0167734.


Bostad WRicketts TA, Stotz PJ, Ross R. (2016). Cardiovascular disease risk in obese adults assessed using established values for cardiorespiratory fitnessApplied Physiology, Nutrition, and Metabolism. 42:93-95.


Rickets TA, Sui X, Lavie CJ, Blair SN, Ross R. (2016). Addition of cardiorespiratory fitness within an obesity risk classification model identified men at increased risk of all-cause mortalityThe American Journal of Medicine. 129: 536.e13-536.e20


Ross R. (2016). Is setting a criterion for “clinically significant weight loss” necessary? Obesity. 24(4): 791. 


Ross R, Blair SN, Arena R, et al. (2016). Importance of assessing cardiorespiratory fitness in clinical practice: a case for fitness as a clinical vital sign: a scientific statement from the American Heart Association. Circulation. 134:653–699. 


Ross R, de Lannoy L, Stotz PJ. (2015). Separate effects of intensity and amount of exercise on individual cardiorespiratory fitness responseMayo Clinic Proceedings. 90(11):1506-1514.


Ross R, Hudson R, Stotz PJ, Lam M. (2015). Effects of exercise amount and intensity on abdominal obesity and glucose tolerance in obese adults: a randomized trialAnnals of Internal Medicine. 162: 325-334. 

Lifestyle and Cardiometabolic Research Unit

28 Division St. RM500

Kingston ON Canada

K7L 3N6

Dr. Robert Ross

Tel: 613-533-6583

Office: KHS 301E

Muscle Physiology Lab




Islam H., Siemens T. L., Matusiak J. B. L.Sawula L., Bonafiglia J. T.,  Preobrazenski N., Jung M. E., and Gurd B. J. (2019) Cardiorespiratory fitness and muscular endurance responses immediately and two-months after a whole-body Tabata or vigorous-intensity continuous training interventionAPNM. 

Preobrazenski N., Islam H., Drouin P. J., Bonafiglia J. T., Tschakovsky M. E., and Gurd B. J. (2019) A novel gravity-induced blood flow restriction model augments ACC phosphorylation and PGC-1α mRNA in human skeletal muscle following aerobic exercise: A randomized crossover studyAPNM 

Islam H., Bonafiglia J. T., Turnbull P. C., Simpson C. A., Perry C. G. R., and Gurd B. J. (2019) The impact of acute and chronic exercise on Nrf2 expression in relation to markers of mitochondrial biogenesis in human skeletal muscleEur. J. App. Physiol. 

Del Giudice M., Bonafiglia J. T., Islam H., Preobrazenski N., Amato A., and Gurd B. J. (2019) Investigating the reproducibility of maximal oxygen uptake responses to high-intensity interval trainingJ. Sci. Med. Sport. 

Bonafiglia J. T., Brennan A.M., Ross R., and Gurd B. J. (2019) An appraisal of the SDIR as an estimate of true individual differences in training responsiveness in parallel-arm exercise randomized controlled trialsPhys. Reports. 7(14):e14163.

Islam H., Hood D. A., and Gurd B. J. (2019) Looking beyond PGC-1α: Emerging regulators of exercise-induced skeletal muscle mitochondrial biogenesis and their activation by dietary compoundsAPNM

Walsh J. J., Bonafiglia J. T., Goldfield G. S., Sigal R. J., Kenny G. P., Doucette S., Hadjiyannakis S., Alberga A. S., and Gurd B. J. (2019) Interindividual variability and individual responses to exercise training in adolescents with obesityAPNM

Bonafiglia J. T., Menzies K.J., and Gurd B. J. (2019) Gene expression variability in human skeletal muscle transcriptome responses to acute resistance exercise. Exp. Phys. 104(5):625-29

Bonafiglia J.T., Ross R., and Gurd B.J. (2019) The application of repeated testing and monoexponential regressions to classify individual cardiorespiratory fitness responses to exercise training. Eur. J. Appl. Phys. 119(4):889-900.

Islam H., Edgett B.A., Bonafiglia J.T., Shulman T., Ma A., Quadrilatero J., Simpson C.A., and Gurd B.J. (2019) Repeatability of exercise-induced changes in mRNA expression and technical considerations for qPCR analysis in human skeletal muscle. Exp. Phys. 104(3):407-420.


Bonafiglia J.T., Nelms M.W., Preobrazenski N., LeBlanc C., Robins L., Su L., Lithopoulos A.,  Walsh J.J., and Gurd B.J. (2018) Moving beyond threshold-based dichotomous to improve the accuracy in classifying non-respondersPhys. Reports 22: e13928.

Preobrazenski N., Bonafiglia J.T., Nelms M.W., Lu S., Robins L. LeBlanc C., and Gurd B.J. (2018) Does lactate predict the chronic adaptive response to training: A comparison of traditional and talk test prescription methodsAPNM 

Edgett B.A., Bonafiglia J.T., Raleigh J.P.Rotundo M.P., Giles M.D., Whittall J.P. and Gurd B.J. (2018) Reproducibility of peak oxygen consumption and the impact of test variability on classification of individual training responses in young recreationally active adultsClin Physiol Funct Image 38: 630-38.

Gurd B.J., Jugal P., Edgett B.A., Scribbans T.D., Quadrilatero J., and Fischer S.L. (2018) The efficacy of a whole body sprint-interval training intervention in an office setting: A feasibility studyWork 60: 295-301

Raleigh J.P., Giles M.D., Islam H., Nelms M.W., Bentley R.F., Jones J.H., Neder J.A., Boonstra K., Quadrilatero J., Simpson C.A., Tschakovsky M.E., and Gurd B.J. (2018) Contribution of central and peripheral adaptations to changes in maximal oxygen uptake following 4 weeks of sprint interval trainingAPNM 43: 1059-1068

Islam H., Edgett B.A. and Gurd B.J. (2018) Coordination of mitochondrial biogenesis by PGC-1α in human skeletal muscle: a re-evaluationMetabolism 79: 42-51

Bonafiglia J.T.Sawula L.J. and Gurd B.J. (2018) An examination of the Counting Talk Test’s ability to discern individual variability in exercise-induced metabolic stressMeasure Phys Ed Ex Sci 22: 38-47

Queen's Muscle Physiology Lab

28 Division St. RM405, Kingston, ON, 37L 3N6

Human Vascular Control Laboratory



Recent Publications

Recent Publications:

Bentley RFJones JHHirai DMZelt JTGiles MDRaleigh JPQuadrilatero JGurd BJNeder JATschakovsky ME. Do interindividual differences in cardiac output during submaximal exercise explain differences in exercising muscle oxygenation and ratings of perceived exertion? Physiol Rep 6: e13570, 2018.

Walsh JJBentley RFGurd BJTschakovsky ME. Short-duration maximal and long-duration submaximal effort forearm exercise achieve elevations in serum brain-derived neurotrophic factor. Front Physiol 8: 1–10, 2017.

Bentley RFWalsh JJDrouin PJVelickovic AKitner SJFenuta AMTschakovsky ME. Dietary nitrate restores compensatory vasodilation and exercise capacity in response to a compromise in oxygen delivery in the noncompensator phenotype. J Appl Physiol 123: 594–605, 2017.

Bentley RFWalsh JJDrouin PJVelickovic AKitner SJFenuta AMTschakovsky ME. Absence of compensatory vasodilation with perfusion pressure challenge in exercise: evidence for and implications of the non-compensator phenotype. J. Appl. Physiol. (2017). doi: 10.1152/japplphysiol.00952.2016.

Walsh JJScribbans TDBentley RFKellawan JMGurd BTschakovsky ME. Neurotrophic growth factor responses to lower body resistance training in older adults. Appl Physiol Nutr Metab 41: 315–323, 2016.

Walsh JJEdgett BATschakovsky MEGurd BJ. Fasting and exercise differentially regulate BDNF mRNA expression in human skeletal muscle. Appl Physiol Nutr Metab 40: 96–98, 2015.